Labbox thermal cycler, DLAB, TC1000
The Labbox thermal cycler is widely used in modern molecular biology laboratories, especially when it comes to amplifying DNA or RNA samples using the polymerase chain reaction (PCR). Compared to other devices on the market, this thermal cycler offers very precise temperature control and impresses with fast heating and cooling rates. This allows experiments to be carried out efficiently and reliable results to be achieved, which is crucial for accurate and reproducible results in today's research environment.
State-of-the-art technology for precise temperature control
The robust design and sophisticated temperature management make this device a reliable part of any laboratory that demands high levels of accuracy, reproducibility and speed. An aluminum block for up to 96 reaction tubes (0.2 ml) ensures flexible application options. Whether 96-well plate, strips with eight or twelve PCR tubes or individual PCR tubes - uniform heat distribution always ensures identical conditions in all samples. A particularly noteworthy feature is the six high-performance Peltier elements, which ensure a constant and homogeneous temperature and enable rapid temperature changes if required.
The thermal cycler covers a wide temperature range from 4 to 105 °C, making it suitable for a variety of applications. The maximum heating and cooling rate is 3 °C per second, minimizing reaction times and increasing throughput and efficiency in the laboratory. The height-adjustable thermal lid with anti-evaporation function prevents condensation. In addition, an intuitive LCD touchscreen facilitates operation by clearly displaying all important information such as current temperature, remaining cycles and programmed segments.
A practical feature is the dual temperature control system, which takes into account either the direct block temperature or the approximate temperature inside the reaction vessels. This allows the ideal programming profile to be selected depending on requirements. In addition, an automatic function check system provides reliable process control and prevents unwanted incorrect measurements or program aborts by reacting immediately to irregularities.
Technical details at a glance
- Thermal block for 96 x 0.2 ml PCR tubes
- Temperature range: 4 - 105 °C
- Lid temperature: 30 - 110 °C
- Accuracy [at 55 °C]: ±0.3 °C
- Maximum heating/cooling rate: 3 °C/second
- Six high-performance Peltier elements for even heat distribution
- Height-adjustable lid with anti-evaporation function
Thanks to these specifications, even complex PCR protocols can be implemented effortlessly. Programmable settings such as time and temperature segments, the creation of differentiated cycles and an archiving system with up to 16 folders and 16 archives per folder make work easier, especially in laboratories with high throughputs. Each protocol configuration is reliably backed up by the robust memory management and can be easily restored even after a power failure.
Certifications and standards
The thermal cycler complies with the applicable safety and quality standards and is generally CE-compliant. As a laboratory device with high quality requirements, it meets additional industry standards so that users can rely on a safe and reliable working environment. This makes it suitable for routine analyses as well as demanding research projects.
Concrete application examples
- Standard PCR: For the amplification of DNA fragments in routine tests
- RT-PCR: For applications in the field of RNA analysis, for example for virus detection
- Genotyping: For the identification of specific gene sequences in clinical or forensic samples
- Cloning preparation: Support for inserting a desired sequence into an expression or vector system
With its highly reliable temperature control and rapid adaptability to different cycle programs, the device extends the range of applications from simple amplifications to complex multiplex PCR protocols. Reactive substances such as Taq polymerase, dNTPs or master mix complete solutions can be used without any problems.
FAQ
How is the thermal lid set?
The thermal lid is height-adjustable and can be adapted to the height of different PCR tubes using a simple adjusting screw or hinge adjustment. This helps to reduce condensation and evaporation.
Which sample formats are best suited
The aluminum block is designed for standard 0.2 ml PCR tubes and also accommodates 96-well plates and strips with eight or twelve tubes. This means it can be flexibly adapted to different experiment designs.
How many programs can be stored
The device has an advanced archiving system with up to 30 segments and 99 cycles per program. In addition, 16 folders and 16 archives per folder can be created to manage different projects or task areas in a structured manner.
Is the thermal cycler compatible with all PCR reagents?
The thermal cycler works with most commercially available PCR reagents and master mixes. Special polymers or enzymes are reliably activated by the precise temperature control and even heat distribution.
What maintenance work is required?
Maintenance is usually limited to regular functional checks via the internal diagnostic system and occasional inspections of the fan and lid seals. A built-in self-test function offers additional safety.
Conclusion
This device impresses with an outstanding combination of flexibility, ease of use and precision. Users benefit from fast cycle times, homogeneous temperature distribution and a wide range of programming and archiving options. If you are looking for a reliable tool for DNA and RNA amplification and other temperature-sensitive reactions, the Labbox thermal cycler is the ideal choice. The robust design, LCD touchscreen and dual temperature control system ensure consistent and reproducible results. This covers a wide range of molecular biology applications and continuously increases efficiency in the laboratory.
